diff --git a/GPU/GLES/FragmentShaderGenerator.cpp b/GPU/GLES/FragmentShaderGenerator.cpp
index c105d90c20..3bab172e2f 100644
--- a/GPU/GLES/FragmentShaderGenerator.cpp
+++ b/GPU/GLES/FragmentShaderGenerator.cpp
@@ -253,7 +253,7 @@ ReplaceBlendType ReplaceBlendWithShader(bool allowShaderBlend) {
 
 	case GE_BLENDMODE_MIN:
 	case GE_BLENDMODE_MAX:
-		if (gl_extensions.EXT_blend_minmax || gl_extensions.GLES3) {
+		if (gstate_c.Supports(GPU_SUPPORTS_BLEND_MINMAX)) {
 			return REPLACE_BLEND_STANDARD;
 		} else {
 			return !allowShaderBlend ? REPLACE_BLEND_STANDARD : REPLACE_BLEND_COPY_FBO;
diff --git a/GPU/GLES/Framebuffer.cpp b/GPU/GLES/Framebuffer.cpp
index d02e0a1145..533649965b 100644
--- a/GPU/GLES/Framebuffer.cpp
+++ b/GPU/GLES/Framebuffer.cpp
@@ -1296,7 +1296,7 @@ void FramebufferManager::BlitFramebuffer(VirtualFramebuffer *dst, int dstX, int
 		useBlit = true;
 	}
 #else
-	if (gl_extensions.GLES3 || (gstate_c..Supports(GPU_SUPPORTS_NV_FRAMEBUFFER_BLIT)) {
+	if (gl_extensions.GLES3 || gstate_c.Supports(GPU_SUPPORTS_NV_FRAMEBUFFER_BLIT)) {
 		useNV = !gl_extensions.GLES3;
 		useBlit = true;
 	}
diff --git a/GPU/GLES/Framebuffer.h b/GPU/GLES/Framebuffer.h
index ee371cbcdc..27b784807f 100644
--- a/GPU/GLES/Framebuffer.h
+++ b/GPU/GLES/Framebuffer.h
@@ -145,6 +145,8 @@ private:
 
 	void SetNumExtraFBOs(int num);
 
+	inline bool ShouldDownloadUsingCPU(const VirtualFramebuffer *vfb) const;
+
 #ifndef USING_GLES2
 	void PackFramebufferAsync_(VirtualFramebuffer *vfb);
 #endif
diff --git a/GPU/GLES/GLES_GPU.cpp b/GPU/GLES/GLES_GPU.cpp
index cf33f6e4dd..c69fea9df6 100644
--- a/GPU/GLES/GLES_GPU.cpp
+++ b/GPU/GLES/GLES_GPU.cpp
@@ -21,6 +21,7 @@
 
 #include "Common/ChunkFile.h"
 
+#include "Core/Config.h"
 #include "Core/Debugger/Breakpoints.h"
 #include "Core/MemMapHelpers.h"
 #include "Core/Host.h"
@@ -31,6 +32,7 @@
 #include "GPU/GPUState.h"
 #include "GPU/ge_constants.h"
 #include "GPU/GeDisasm.h"
+#include "GPU/Common/FramebufferCommon.h"
 
 #include "GPU/GLES/ShaderManager.h"
 #include "GPU/GLES/GLES_GPU.h"
@@ -470,13 +472,14 @@ void GLES_GPU::CheckGPUFeatures() {
 	if (gl_extensions.ARB_blend_func_extended /*|| gl_extensions.EXT_blend_func_extended*/)
 		features |= GPU_SUPPORTS_DUALSOURCE_BLEND;
 
-#ifdef USING_GLES2
-	if (gl_extensions.GLES3)
-		features |= GPU_SUPPORTS_GLSL_ES_300;
-#else
-	if (gl_extensions.VersionGEThan(3, 3, 0))
-		features |= GPU_SUPPORTS_GLSL_330;
-#endif
+	if (gl_extensions.IsGLES) {
+		if (gl_extensions.GLES3)
+			features |= GPU_SUPPORTS_GLSL_ES_300;
+	} else {
+		if (gl_extensions.VersionGEThan(3, 3, 0))
+			features |= GPU_SUPPORTS_GLSL_330;
+	}
+
 	// Framebuffer fetch appears to be buggy at least on Tegra 3 devices.  So we blacklist it.
 	// Tales of Destiny 2 has been reported to display green.
 	if (gl_extensions.EXT_shader_framebuffer_fetch || gl_extensions.NV_shader_framebuffer_fetch || gl_extensions.ARM_shader_framebuffer_fetch) {
@@ -491,27 +494,45 @@ void GLES_GPU::CheckGPUFeatures() {
 		features |= GPU_SUPPORTS_FBO_ARB;
 	}
 
+	bool useCPU = false;
+	if (!gl_extensions.IsGLES) {
+		// Urrgh, we don't even define FB_READFBOMEMORY_CPU on mobile
 #ifndef USING_GLES2
-	bool useCPU = g_Config.iRenderingMode == FB_READFBOMEMORY_CPU;
-	// We might get here if hackForce04154000Download_ is hit.
-	// Some cards or drivers seem to always dither when downloading a framebuffer to 16-bit.
-	// This causes glitches in games that expect the exact values.
-	// It has not been experienced on NVIDIA cards, so those are left using the GPU (which is faster.)
-	if (g_Config.iRenderingMode == FB_BUFFERED_MODE) {
-		if (gl_extensions.gpuVendor != GPU_VENDOR_NVIDIA || gl_extensions.ver[0] < 3) {
-			useCPU = true;
-		}
-	}
-#else
-	useCPU = true;
+		useCPU = g_Config.iRenderingMode == FB_READFBOMEMORY_CPU;
 #endif
-	if (useCPU) {
-		features |= GPU_PREFER_CPU_DOWNLOAD;
+		// We might get here if hackForce04154000Download_ is hit.
+		// Some cards or drivers seem to always dither when downloading a framebuffer to 16-bit.
+		// This causes glitches in games that expect the exact values.
+		// It has not been experienced on NVIDIA cards, so those are left using the GPU (which is faster.)
+		if (g_Config.iRenderingMode == FB_BUFFERED_MODE) {
+			if (gl_extensions.gpuVendor != GPU_VENDOR_NVIDIA || gl_extensions.ver[0] < 3) {
+				useCPU = true;
+			}
+		}
+	} else {
+		useCPU = true;
 	}
 
+	if (useCPU)
+		features |= GPU_PREFER_CPU_DOWNLOAD;
+
 	if ((gl_extensions.gpuVendor == GPU_VENDOR_NVIDIA) || (gl_extensions.gpuVendor == GPU_VENDOR_AMD))
 		features |= GPU_PREFER_REVERSE_COLOR_ORDER;
 
+	if (gl_extensions.OES_texture_npot)
+		features |= GPU_SUPPORTS_OES_TEXTURE_NPOT;
+
+	if (gl_extensions.EXT_unpack_subimage || !gl_extensions.IsGLES)
+		features |= GPU_SUPPORTS_UNPACK_SUBIMAGE;
+
+	if (gl_extensions.EXT_blend_minmax || gl_extensions.GLES3)
+		features |= GPU_SUPPORTS_BLEND_MINMAX;
+
+#ifdef MOBILE_DEVICE
+	// Arguably, we should turn off GPU_IS_MOBILE on like modern Tegras, etc.
+	features |= GPU_IS_MOBILE;
+#endif
+
 	gstate_c.featureFlags = features;
 }
 
diff --git a/GPU/GLES/GLES_GPU.h b/GPU/GLES/GLES_GPU.h
index 178770837d..b2a97684e1 100644
--- a/GPU/GLES/GLES_GPU.h
+++ b/GPU/GLES/GLES_GPU.h
@@ -37,6 +37,7 @@ public:
 	GLES_GPU();
 	~GLES_GPU();
 
+	// This gets called on startup and when we get back from settings.
 	void CheckGPUFeatures();
 
 	void InitClear() override;
diff --git a/GPU/GLES/StateMapping.cpp b/GPU/GLES/StateMapping.cpp
index bf46f1a4bc..7c08adc418 100644
--- a/GPU/GLES/StateMapping.cpp
+++ b/GPU/GLES/StateMapping.cpp
@@ -567,7 +567,7 @@ void TransformDrawEngine::ApplyBlendState() {
 		glstate.blendFuncSeparate.set(glBlendFuncA, glBlendFuncB, GL_ZERO, GL_ONE);
 	}
 
-	if (gl_extensions.EXT_blend_minmax || gl_extensions.GLES3) {
+	if (gstate_c.Supports(GPU_SUPPORTS_BLEND_MINMAX)) {
 		glstate.blendEquationSeparate.set(eqLookup[blendFuncEq], alphaEq);
 	} else {
 		glstate.blendEquationSeparate.set(eqLookupNoMinMax[blendFuncEq], alphaEq);
diff --git a/GPU/GLES/TextureCache.cpp b/GPU/GLES/TextureCache.cpp
index d953087a89..ff352ca552 100644
--- a/GPU/GLES/TextureCache.cpp
+++ b/GPU/GLES/TextureCache.cpp
@@ -66,6 +66,7 @@
 #define GL_UNPACK_ROW_LENGTH 0x0CF2
 #endif
 
+// Hack!
 extern int g_iNumVideos;
 
 TextureCache::TextureCache() : cacheSizeEstimate_(0), secondCacheSizeEstimate_(0), clearCacheNextFrame_(false), lowMemoryMode_(false), clutBuf_(NULL), clutMaxBytes_(0), texelsScaledThisFrame_(0) {
@@ -1446,14 +1447,15 @@ void TextureCache::SetTexture(bool force) {
 			scaleFactor = (PSP_CoreParameter().renderWidth + 479) / 480;
 		}
 
-#ifndef MOBILE_DEVICE
-		scaleFactor = std::min(gl_extensions.OES_texture_npot ? 5 : 4, scaleFactor);
-		if (!gl_extensions.OES_texture_npot && scaleFactor == 3) {
-			scaleFactor = 2;
+		// Mobile devices don't get the higher scale factors, too expensive. Very rough way to decide though...
+		if (!gstate_c.Supports(GPU_IS_MOBILE)) {
+			scaleFactor = std::min(gstate_c.Supports(GPU_SUPPORTS_OES_TEXTURE_NPOT) ? 5 : 4, scaleFactor);
+			if (!gl_extensions.OES_texture_npot && scaleFactor == 3) {
+				scaleFactor = 2;
+			}
+		} else {
+			scaleFactor = std::min(gstate_c.Supports(GPU_SUPPORTS_OES_TEXTURE_NPOT) ? 3 : 2, scaleFactor);
 		}
-#else
-		scaleFactor = std::min(gl_extensions.OES_texture_npot ? 3 : 2, scaleFactor);
-#endif
 	} else {
 		scaleFactor = g_Config.iTexScalingLevel;
 	}
@@ -1698,7 +1700,7 @@ void *TextureCache::DecodeTextureLevel(GETextureFormat format, GEPaletteFormat c
 	case GE_TFMT_8888:
 		if (!swizzled) {
 			// Special case: if we don't need to deal with packing, we don't need to copy.
-			if ((g_Config.iTexScalingLevel == 1 && gl_extensions.EXT_unpack_subimage) || w == bufw) {
+			if ((g_Config.iTexScalingLevel == 1 && gstate_c.Supports(GPU_SUPPORTS_UNPACK_SUBIMAGE)) || w == bufw) {
 				if (UseBGRA8888()) {
 					tmpTexBuf32.resize(std::max(bufw, w) * h);
 					finalBuf = tmpTexBuf32.data();
@@ -1791,7 +1793,7 @@ void *TextureCache::DecodeTextureLevel(GETextureFormat format, GEPaletteFormat c
 		ERROR_LOG_REPORT(G3D, "NO finalbuf! Will crash!");
 	}
 
-	if (!(g_Config.iTexScalingLevel == 1 && gl_extensions.EXT_unpack_subimage) && w != bufw) {
+	if (!(g_Config.iTexScalingLevel == 1 && gstate_c.Supports(GPU_SUPPORTS_UNPACK_SUBIMAGE)) && w != bufw) {
 		int pixelSize;
 		switch (dstFmt) {
 		case GL_UNSIGNED_SHORT_4_4_4_4:
@@ -1803,6 +1805,7 @@ void *TextureCache::DecodeTextureLevel(GETextureFormat format, GEPaletteFormat c
 			pixelSize = 4;
 			break;
 		}
+
 		// Need to rearrange the buffer to simulate GL_UNPACK_ROW_LENGTH etc.
 		int inRowBytes = bufw * pixelSize;
 		int outRowBytes = w * pixelSize;
@@ -1868,7 +1871,7 @@ void TextureCache::LoadTextureLevel(TexCacheEntry &entry, int level, bool replac
 	gpuStats.numTexturesDecoded++;
 
 	// Can restore these and remove the fixup at the end of DecodeTextureLevel on desktop GL and GLES 3.
-	if ((g_Config.iTexScalingLevel == 1 && gl_extensions.EXT_unpack_subimage) && w != bufw) {
+	if ((g_Config.iTexScalingLevel == 1 && gstate_c.Supports(GPU_SUPPORTS_UNPACK_SUBIMAGE)) && w != bufw) {
 		glPixelStorei(GL_UNPACK_ROW_LENGTH, bufw);
 		useUnpack = true;
 	}
diff --git a/GPU/GPUCommon.h b/GPU/GPUCommon.h
index cc60d15080..6ead754b81 100644
--- a/GPU/GPUCommon.h
+++ b/GPU/GPUCommon.h
@@ -18,6 +18,8 @@ class GPUCommon : public GPUThreadEventQueue, public GPUDebugInterface {
 public:
 	GPUCommon();
 	virtual ~GPUCommon();
+
+	virtual void CheckGPUFeatures() override {}
 	virtual void Reinitialize();
 
 	virtual void InterruptStart(int listid);
diff --git a/GPU/GPUInterface.h b/GPU/GPUInterface.h
index 15a57fed3c..9af5d02ba0 100644
--- a/GPU/GPUInterface.h
+++ b/GPU/GPUInterface.h
@@ -207,6 +207,8 @@ public:
 
 	static const int DisplayListMaxCount = 64;
 
+	virtual void CheckGPUFeatures() = 0;
+
 	// Initialization
 	virtual void InitClear() = 0;
 	virtual void Reinitialize() = 0;
diff --git a/GPU/GPUState.h b/GPU/GPUState.h
index 1e639e4f26..e70fbb48c1 100644
--- a/GPU/GPUState.h
+++ b/GPU/GPUState.h
@@ -448,9 +448,13 @@ enum {
 	GPU_SUPPORTS_DUALSOURCE_BLEND = FLAG_BIT(0),
 	GPU_SUPPORTS_GLSL_ES_300 = FLAG_BIT(1),
 	GPU_SUPPORTS_GLSL_330 = FLAG_BIT(2),
+	GPU_SUPPORTS_UNPACK_SUBIMAGE = FLAG_BIT(3),
+	GPU_SUPPORTS_BLEND_MINMAX = FLAG_BIT(4),
 	GPU_SUPPORTS_NV_FRAMEBUFFER_BLIT = FLAG_BIT(10),
 	GPU_SUPPORTS_ANY_FRAMEBUFFER_FETCH = FLAG_BIT(20),
 	GPU_SUPPORTS_FBO_ARB = FLAG_BIT(25),
+	GPU_SUPPORTS_OES_TEXTURE_NPOT = FLAG_BIT(26),
+	GPU_IS_MOBILE = FLAG_BIT(29),
 	GPU_PREFER_CPU_DOWNLOAD = FLAG_BIT(30),
 	GPU_PREFER_REVERSE_COLOR_ORDER = FLAG_BIT(31),
 };
diff --git a/UI/EmuScreen.cpp b/UI/EmuScreen.cpp
index 8b2db8bdc0..2bbc151f21 100644
--- a/UI/EmuScreen.cpp
+++ b/UI/EmuScreen.cpp
@@ -180,6 +180,7 @@ void EmuScreen::dialogFinished(const Screen *dialog, DialogResult result) {
 		quit_ = false;
 	}
 	RecreateViews();
+	gpu->CheckGPUFeatures();
 }
 
 static void AfterStateLoad(bool success, void *ignored) {