diff --git a/Core/MIPS/ARM64/Arm64Asm.cpp b/Core/MIPS/ARM64/Arm64Asm.cpp
index 1abf148d7c..755e35f57c 100644
--- a/Core/MIPS/ARM64/Arm64Asm.cpp
+++ b/Core/MIPS/ARM64/Arm64Asm.cpp
@@ -247,6 +247,9 @@ void Arm64Jit::GenerateFixedCode(const JitOptions &jo) {
 			}
 
 			LDR(INDEX_UNSIGNED, SCRATCH1, CTXREG, offsetof(MIPSState, pc));
+#ifdef MASKED_PSP_MEMORY
+			ANDI2R(SCRATCH1, SCRATCH1, 0x3FFFFFFF);
+#endif
 			LDR(SCRATCH1, MEMBASEREG, SCRATCH1_64);
 			LSR(SCRATCH2, SCRATCH1, 24);   // or UBFX(SCRATCH2, SCRATCH1, 24, 8)
 			ANDI2R(SCRATCH1, SCRATCH1, 0x00FFFFFF);
diff --git a/Core/MIPS/ARM64/Arm64CompALU.cpp b/Core/MIPS/ARM64/Arm64CompALU.cpp
index aa3ffb577e..f97ba0dee7 100644
--- a/Core/MIPS/ARM64/Arm64CompALU.cpp
+++ b/Core/MIPS/ARM64/Arm64CompALU.cpp
@@ -43,7 +43,7 @@ using namespace MIPSAnalyst;
 // All functions should have CONDITIONAL_DISABLE, so we can narrow things down to a file quickly.
 // Currently known non working ones should have DISABLE.
 
-// #define CONDITIONAL_DISABLE { Comp_Generic(op); return; }
+//#define CONDITIONAL_DISABLE(flag) { Comp_Generic(op); return; }
 #define CONDITIONAL_DISABLE(flag) if (jo.Disabled(JitDisable::flag)) { Comp_Generic(op); return; }
 #define DISABLE { Comp_Generic(op); return; }
 
diff --git a/Core/MIPS/ARM64/Arm64CompFPU.cpp b/Core/MIPS/ARM64/Arm64CompFPU.cpp
index 98121615b1..efe6887f23 100644
--- a/Core/MIPS/ARM64/Arm64CompFPU.cpp
+++ b/Core/MIPS/ARM64/Arm64CompFPU.cpp
@@ -51,7 +51,7 @@
 // All functions should have CONDITIONAL_DISABLE, so we can narrow things down to a file quickly.
 // Currently known non working ones should have DISABLE.
 
-// #define CONDITIONAL_DISABLE { Comp_Generic(op); return; }
+// #define CONDITIONAL_DISABLE(flag) { Comp_Generic(op); return; }
 #define CONDITIONAL_DISABLE(flag) if (jo.Disabled(JitDisable::flag)) { Comp_Generic(op); return; }
 #define DISABLE { Comp_Generic(op); return; }
 
@@ -102,7 +102,11 @@ void Arm64Jit::Comp_FPULS(MIPSOpcode op)
 		fpr.SpillLock(ft);
 		fpr.MapReg(ft, MAP_NOINIT | MAP_DIRTY);
 		if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+			u32 addr = (offset + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 			u32 addr = offset + gpr.GetImm(rs);
+#endif
 			gpr.SetRegImm(SCRATCH1, addr);
 		} else {
 			gpr.MapReg(rs);
@@ -129,7 +133,11 @@ void Arm64Jit::Comp_FPULS(MIPSOpcode op)
 
 		fpr.MapReg(ft);
 		if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+			u32 addr = (offset + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 			u32 addr = offset + gpr.GetImm(rs);
+#endif
 			gpr.SetRegImm(SCRATCH1, addr);
 		} else {
 			gpr.MapReg(rs);
diff --git a/Core/MIPS/ARM64/Arm64CompLoadStore.cpp b/Core/MIPS/ARM64/Arm64CompLoadStore.cpp
index e322d4a9a7..a4d647d98b 100644
--- a/Core/MIPS/ARM64/Arm64CompLoadStore.cpp
+++ b/Core/MIPS/ARM64/Arm64CompLoadStore.cpp
@@ -41,7 +41,7 @@
 // All functions should have CONDITIONAL_DISABLE, so we can narrow things down to a file quickly.
 // Currently known non working ones should have DISABLE.
 
-// #define CONDITIONAL_DISABLE { Comp_Generic(op); return; }
+//#define CONDITIONAL_DISABLE(flag) { Comp_Generic(op); return; }
 #define CONDITIONAL_DISABLE(flag) if (jo.Disabled(JitDisable::flag)) { Comp_Generic(op); return; }
 #define DISABLE { Comp_Generic(op); return; }
 
@@ -56,6 +56,9 @@ namespace MIPSComp {
 		} else {
 			MOV(SCRATCH1, gpr.R(rs));
 		}
+#ifdef MASKED_PSP_MEMORY
+		ANDI2R(SCRATCH1, SCRATCH1, 0x3FFFFFFF);
+#endif
 	}
 
 	std::vector<FixupBranch> Arm64Jit::SetScratch1ForSafeAddress(MIPSGPReg rs, s16 offset, ARM64Reg tempReg) {
@@ -135,12 +138,17 @@ namespace MIPSComp {
 		std::vector<FixupBranch> skips;
 
 		if (gpr.IsImm(rs) && Memory::IsValidAddress(iaddr)) {
+#ifdef MASKED_PSP_MEMORY
+			u32 addr = iaddr & 0x3FFFFFFF;
+#else
+			u32 addr = iaddr;
+#endif
 			// Need to initialize since this only loads part of the register.
 			// But rs no longer matters (even if rs == rt) since we have the address.
 			gpr.MapReg(rt, load ? MAP_DIRTY : 0);
-			gpr.SetRegImm(SCRATCH1, iaddr & ~3);
+			gpr.SetRegImm(SCRATCH1, addr & ~3);
 
-			u8 shift = (iaddr & 3) * 8;
+			u8 shift = (addr & 3) * 8;
 
 			switch (o) {
 			case 34: // lwl
@@ -347,7 +355,12 @@ namespace MIPSComp {
 			}
 
 			if (gpr.IsImm(rs) && Memory::IsValidAddress(iaddr)) {
-				if (offset == 0) {
+#ifdef MASKED_PSP_MEMORY
+				u32 addr = iaddr & 0x3FFFFFFF;
+#else
+				u32 addr = iaddr;
+#endif
+				if (addr == iaddr && offset == 0) {
 					// It was already safe.  Let's shove it into a reg and use it directly.
 					if (targetReg == INVALID_REG) {
 						load ? gpr.MapDirtyIn(rt, rs) : gpr.MapInIn(rt, rs);
@@ -360,7 +373,7 @@ namespace MIPSComp {
 						gpr.MapReg(rt, load ? MAP_NOINIT : 0);
 						targetReg = gpr.R(rt);
 					}
-					gpr.SetRegImm(SCRATCH1, iaddr);
+					gpr.SetRegImm(SCRATCH1, addr);
 					addrReg = SCRATCH1;
 				}
 			} else {
diff --git a/Core/MIPS/ARM64/Arm64CompVFPU.cpp b/Core/MIPS/ARM64/Arm64CompVFPU.cpp
index cf67f4d84f..22b618aaea 100644
--- a/Core/MIPS/ARM64/Arm64CompVFPU.cpp
+++ b/Core/MIPS/ARM64/Arm64CompVFPU.cpp
@@ -37,7 +37,7 @@
 // All functions should have CONDITIONAL_DISABLE, so we can narrow things down to a file quickly.
 // Currently known non working ones should have DISABLE.
 
-// #define CONDITIONAL_DISABLE { fpr.ReleaseSpillLocksAndDiscardTemps(); Comp_Generic(op); return; }
+// #define CONDITIONAL_DISABLE(flag) { fpr.ReleaseSpillLocksAndDiscardTemps(); Comp_Generic(op); return; }
 #define CONDITIONAL_DISABLE(flag) if (jo.Disabled(JitDisable::flag)) { Comp_Generic(op); return; }
 #define DISABLE { fpr.ReleaseSpillLocksAndDiscardTemps(); Comp_Generic(op); return; }
 
@@ -222,7 +222,11 @@ namespace MIPSComp {
 			// CC might be set by slow path below, so load regs first.
 			fpr.MapRegV(vt, MAP_DIRTY | MAP_NOINIT);
 			if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+				u32 addr = (offset + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 				u32 addr = offset + gpr.GetImm(rs);
+#endif
 				gpr.SetRegImm(SCRATCH1, addr);
 			} else {
 				gpr.MapReg(rs);
@@ -251,7 +255,11 @@ namespace MIPSComp {
 			// CC might be set by slow path below, so load regs first.
 			fpr.MapRegV(vt);
 			if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+				u32 addr = (offset + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 				u32 addr = offset + gpr.GetImm(rs);
+#endif
 				gpr.SetRegImm(SCRATCH1, addr);
 			} else {
 				gpr.MapReg(rs);
@@ -293,7 +301,11 @@ namespace MIPSComp {
 				fpr.MapRegsAndSpillLockV(vregs, V_Quad, MAP_DIRTY | MAP_NOINIT);
 
 				if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+					u32 addr = (imm + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 					u32 addr = imm + gpr.GetImm(rs);
+#endif
 					gpr.SetRegImm(SCRATCH1_64, addr + (uintptr_t)Memory::base);
 				} else {
 					gpr.MapReg(rs);
@@ -326,7 +338,11 @@ namespace MIPSComp {
 				fpr.MapRegsAndSpillLockV(vregs, V_Quad, 0);
 
 				if (gpr.IsImm(rs)) {
+#ifdef MASKED_PSP_MEMORY
+					u32 addr = (imm + gpr.GetImm(rs)) & 0x3FFFFFFF;
+#else
 					u32 addr = imm + gpr.GetImm(rs);
+#endif
 					gpr.SetRegImm(SCRATCH1_64, addr + (uintptr_t)Memory::base);
 				} else {
 					gpr.MapReg(rs);
diff --git a/Core/MIPS/ARM64/Arm64RegCache.cpp b/Core/MIPS/ARM64/Arm64RegCache.cpp
index dd2c83c302..b089efa309 100644
--- a/Core/MIPS/ARM64/Arm64RegCache.cpp
+++ b/Core/MIPS/ARM64/Arm64RegCache.cpp
@@ -440,6 +440,9 @@ Arm64Gen::ARM64Reg Arm64RegCache::MapRegAsPointer(MIPSGPReg reg) {
 		if (!jo_->enablePointerify) {
 			// Convert to a pointer by adding the base and clearing off the top bits.
 			// If SP, we can probably avoid the top bit clear, let's play with that later.
+#ifdef MASKED_PSP_MEMORY
+			emit_->ANDI2R(EncodeRegTo64(a), EncodeRegTo64(a), 0x3FFFFFFF);
+#endif
 			emit_->ADD(EncodeRegTo64(a), EncodeRegTo64(a), MEMBASEREG);
 			mr[reg].loc = ML_ARMREG_AS_PTR;
 		} else if (!ar[a].pointerified) {